Evaluation of a novel collagen-gelatin scaffold for achieving the sustained release of basic fibroblast growth factor in a diabetic mouse model.

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Kanda, Norikazu; Morimoto, Naoki; Ayvazyan, Artem A; Takemoto, Satoru; Kawai, Katsuya; Nakamura, Yoko; Sakamoto, Yuki; Taira, Tsuguyoshi; Suzuki, Shigehiko;
  • Publisher: wiley
  • Journal: Journal of tissue engineering and regenerative medicine, volume 8, issue 1, pages 29-40 (issn: 1932-7005)
  • Publisher copyright policies & self-archiving
  • Subject: bFGF | artificial skin | collagen–gelatin sponge | scaffold | sustained release | wound healing | diabetic mice

The objective of this study was to evaluate the ability of a scaffold, collagen-gelatin sponge (CGS), to release basic fibroblast growth factor (bFGF) in a sustained manner, using a pressure-induced decubitus ulcer model involving genetically diabetic mice. We confirmed... View more
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