Mouse Models of Graves' Disease

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Nagayama, Yuji;
  • Journal: Acta medica Nagasakiensia,volume 50,issue 2,pages49-53 (issn: 0001-6055)
  • Subject: Cytokine | Autoimmunity | Graves'disease | Adenovirus | Thyrotropinreceptor
    mesheuropmc: endocrine system | endocrine system diseases

Graves' disease is characterized by overstimulation of the thyroid gland with agonistic autoantibodies against the thyrotropin (TSH) receptor, leading to hyperthyroidism and diffuse hyperplasia of the thyroid gland. Our and other laboratories have recently established s... View more
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