publication . Article . 2017

Facile preparation of transparent poly(vinyl alcohol) hydrogels with uniform microcrystalline structure by hot pressing without using organic solvents

Sakaguchi, Tomoyo; Nagano, Shusaku; Hara, Mitsuo; Hyon, Suong-Hyu; Patel, Monika; Matsumura, Kazuaki;
Open Access English
  • Published: 05 Apr 2017 Journal: Polymer Journal, volume 49, pages 535-542 (issn: 0032-3896, Copyright policy)
  • Publisher: Springer Nature
Abstract
Poly(vinyl alcohol) hydrogels (PVA-Hs) are promising materials for various biomedical applications and have been studied extensively. Low-temperature crystallization is the most popular method used to prepare PVA-Hs with excellent mechanical properties. However, this method uses DMSO as a solvent, which is toxic and difficult to handle. In this study, a novel hot pressing method was developed for preparing transparent PVA-Hs in order to eliminate the need of DMSO for solubilizing PVA during gelation. Unlike the conventional methods, this method used high initial concentrations of PVA, which made the molding of the gels easy and enhanced their gelation. The hydro...
Subjects
Medical Subject Headings: integumentary system
free text keywords: biomaterials, crystallization, PVA, hydrogel, artificial cartilage
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Article . 2017
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