Utilization of reconstructed cultured human skin models as an alternative skin for permeation studies of chemical compounds

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Kano, Satoshi; 藤堂, 浩明; 杉江, 謙一; 藤本, 英哲; 中田, 圭一; 徳留, 嘉寛; 橋本, フミ惠; 杉林, 堅次;
(2010)
  • Publisher: 日本動物実験代替法学会
  • Journal: AATEX (Alternatives to Animal Testing and EXperimentation),volume 15,issue 2,pages61-70 (issn: 1344-0411)
  • Publisher copyright policies & self-archiving
  • Subject: alternative membrane | skin permeation | reconstructed human skin models | skin corrosive/irritation
    mesheuropmc: integumentary system

Two reconstructed human skin models, EpiskinSM and EpiDermTM, have been approved as alternative membranes for skin corrosive/irritation experiments due to their close correlation with animal skin. Such reconstructed human skin models were evaluated as alternative membra... View more
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