Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats

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広瀬, 明彦; 山崎, 研; 坂本, 武史; 須永, 克佳; 津田, 整; 光本, 篤史; 工藤, なをみ; 川嶋, 洋一; (2011)
  • Publisher: 日本薬理学会
  • Journal: Journal of Pharmacological Sciences,volume 116,issue 4,pages362-372 (issn: 1347-8648)
  • Subject: Clofibric Acid | 1-Acylglycerophosphocholine | O-Acyltransferase | Oleic Acid | Stearoyl-CoA 9-Desaturase | 肝臓 | 小胞体 | 同位体標識 | Wistarラット | 炭素放射性同位体 | phosphatidylcholine | endoplasmic reticulum

The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic acid (18:1) from stearic acid (18:0) and utilization of the 18:1 formed for phosphatidylcholine (PC) formation in endoplasmic reticulum in the liver of rats were studied... View more
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