Genotoxicity of extracts of Japanese traditional herbal medicines (Kampo)

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Makoto, Katami; Haruo, Kuboniwa; Shunichi, Maemura; Toshihiko, Yanagisawa; New Drug Discovery Laboratory, R & D Division, TSUMURA & Co.; New Drug Discovery Laboratory, R & D Division, TSUMURA & Co.; New Drug Discovery Laboratory, R & D Division, TSUMURA & Co.; New Drug Discovery Laboratory, R & D Division, TSUMURA & Co.;
(2002)
  • Journal: 環境変異原研究 = Environmental mutagen research communication,volume 24,issue 1,pages1-15 (issn: 0910-0865)
  • Subject: Japanese traditional herbal medicines (Kampo) | genotoxicity | Ames test | micronucleus test | unscheduled DNA synthesis test

The possible genotoxicity potential of 128 Japanese traditional herbal medicines (Kampo) was investigated using a bacterial reverse mutation test (the Ames test), an in vivo micronucleus test (MN test) in mouse bone marrow cells and an unscheduled DNA synthesis test (UD... View more
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