Genistein improves spatial learning and memory in male rats with elevated glucose level during memory consolidation

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Kohara, Yumi ; Kawaguchi, Shinichiro ; Kuwahara, Rika ; Uchida, Yutaro ; Oku, Yushi ; Yamashita, Kimihiro (2015)
  • Publisher: Elsevier Inc.
  • Journal: Physiology & Behavior, volume 140, pages 15-22 (issn: 0031-9384)
  • Subject: Genistein | Glucose load | Oral administration | Phytoestrogen | Rat | Spatial learning

Cognitive dysfunction due to higher blood glucose level has been reported previously. Genistein (GEN) is a phytoestrogen that we hypothesized might lead to improved memory, despite elevated blood glucose levels at the time of memory consolidation. To investigate this hy... View more
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