Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma

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Narita, Masato ; Hatano, Etsuro ; Arizono, Shigeki ; Miyagawa-Hayashino, Aya ; Isoda, Hiroyoshi ; Kitamura, Koji ; Yasuchika, Kentaro ; Nitta, Takashi ; Uemoto, Shinji (2009)
  • Publisher: Springer Verlag
  • Journal: Journal of Gastroenterology, volume 44, issue 7, pages 793-798 (issn: 0944-1174)
  • Subject: OATP1B3 | MRI | Green hepatoma | HCC | Gd-EOB-DTPA
    mesheuropmc: respiratory system | cardiovascular system | animal diseases | digestive system diseases | circulatory and respiratory physiology

Background: Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) is an MRI contrast agent with perfusion and hepatoselective properties. The purpose of the study was to examine uptake of Gd-EOB-DTPA in the hepatobiliary phase in hepatocellular carci... View more
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