Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells

Article English OPEN
Baghdadi, Muhammad ; Wada, Haruka ; Nakanishi, Sayaka ; Abe, Hirotake ; Han, Nanumi ; Putra, Wira Eka ; Endo, Daisuke ; Watari, Hidemichi ; Sakuragi, Noriaki ; Hida, Yasuhiro ; Kaga, Kichizo ; Miyagi, Yohei ; Yokose, Tomoyuki ; Takano, Atsushi ; Daigo, Yataro ; Seino, Ken-ichiro (2016)
  • Publisher: American Association for Cancer Research
  • Journal: Cancer research, volume 76, issue 20, pages 6,030-6,042 (issn: 0008-5472)

The ability of tumor cells to escape immune destruction and their acquired resistance to chemotherapy are major obstacles to effective cancer therapy. Although immune checkpoint therapies such as anti-PD-1 address these issues in part, clinical responses remain limited ... View more
Share - Bookmark

  • Download from
    JAIRO via JAIRO (Article, 2016)
  • Cite this publication