Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5′-phosphate-binding protein YggS

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Ito, Tomokazu; Yamauchi, Ayako; Hemmi, Hisashi; Yoshimura, Tohru;
(2016)
  • Publisher: Elsevier
  • Journal: Journal of Bioscience and Bioengineering, volume 122, issue 6, pages 689-693 (issn: 1389-1723)
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  • Subject: Pyridoxal 5′-phosphate | Ophthalmic acid | YggS | Escherichia coli | Glutathione | Amino acid

Escherichia coli YggS is a highly conserved pyridoxal 5′-phosphate (PLP)-binding protein whose biochemical function is currently unknown. A previous study with a yggS-deficient E. coli strain (ΔyggS) demonstrated that YggS controls l-Ile- and l-Val-metabolism by modulat... View more
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