publication . Research . 1998

Factors for the bioavailability of heme iron preparation in female rats

村上, 亜由美; 岸本, 三香子; 川口, 真規子; 松浦, 寿喜; 市川, 富夫; Ayumi, Murakami; Mikako, Kishimoto; Makiko, Kawaguchi; Toshiki, Matsuura; Tomio, Ichikawa;
Open Access Japanese
  • Published: 31 Mar 1998 Journal: 武庫川女子大学紀要. 自然科学編, volume 45, pages 113-118 (issn: 0916-3123, Copyright policy)
Abstract
Factors for iron absorption in small intestine using heme iron preparation (HIP) and ferric citrate (FC) were investigated. We measured the solubility of iron of experimental diets (FC-normal, FC-overload, HIP-normal, HIP-overload) in water (adjusted pH6.8) and the diffusibility of dietary iron after digestion in vitro. The results did not show significantly differences between FC and HIP. Also, we measured microsomal heme oxygenase (HO) activity in intestinal mucosa of female rats fed experimental diets. HO of intestinal mucosa is necessary for iron of HIP to be transported from intestine to blood, but HIP administration did not induced it. It is suggested that...
Subjects
Medical Subject Headings: musculoskeletal diseases
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Research . 1998
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