Measurement of Diffusion Coefficients of Parabens and Steroids in Water and 1-Octanol

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関, 俊暢; 持田, 純子; 岡本, 麻衣子; 細谷, 治; 從二, 和彦; Morimoto, Kazuhiro;
(2003)
  • Publisher: 日本薬学会
  • Journal: Chemical and Pharmaceutical Bulletin,volume 51,issue 6,pages734-736 (issn: 0009-2363)
  • Publisher copyright policies & self-archiving
  • Subject: diffusion coefficient | steroid | paraben | lipophilicity | hydrogen bond

Diffusion coefficients (D) of parabens and steroids in water and 1-octanol were determined by using the chromatographic broadening method at 37 °C, and the relationships between the D values and the physicochemical properties of the drugs were discussed. The D values in... View more
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