Gestational Age-Dependent Increase of Survival Motor Neuron Protein in Umbilical Cord-Derived Mesenchymal Stem CellsArticle English OPEN
Iwatani, Sota; Harahap, Nur Imma Fatimah; Nurputra, Dian Kesumapramudya; Tairaku, Shinya; Shono, Akemi; Kurokawa, Daisuke; Yamana, Keiji; Thwin, Khin Kyae Mon; Yoshida, Makiko; Mizobuchi, Masami; Koda, Tsubasa; Fujioka, Kazumichi; Taniguchi-Ikeda, Mariko; Yamada, Hideto; Morioka, Ichiro; Iijima, Kazumoto; Nishio, Hisahide; Nishimura, Noriyuki; (2017)
- Publisher: Frontiers Media S.A.
- Journal: Frontiers in Pediatrics,volume 5,page194 (issn: 2296-2360, eissn: 2296-2360)
- Related identifiers: , ,
Subject: RJ1-570 | Pediatrics | spinal muscular atrophy | Original Research | umbilical cord-derived mesenchymal stem cell | gestational age | perinatal development | survival motor neuron-targeted therapy
mesheuropmc: nervous system diseases | nervous system | animal diseases
Spinal muscular atrophy (SMA) is the most common genetic neurological disease leading to infant death. It is caused by loss of survival motor neuron (SMN) 1 gene and subsequent reduction of SMN protein in motor neurons. Because SMN is ubiquitously expresse... View more