publication . Article . 2017

The effect of 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid derivative on the activity of lipid peroxidation processes and the antioxidant defense in chronic hypobaric hypoxia

I. I. Zamorskii; Yu. S. Bukataru; S. V. Kolisnyk;
Open Access English
  • Published: 20 Mar 2017 Journal: Клінічна фармація (issn: 1562-725X, Copyright policy)
  • Publisher: National University of Pharmacy
Abstract
Hypoxia is a typical pathological process developing due to the decreased concentration of oxygen in the organism or in the particular tissues and organs, as well as disturbances of oxygen utilization during biological oxidation.Aim. To determine the antihypoxic and antioxidant activity of the ZNM derivative of 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid in the brain and blood plasma of rats under the conditions of chronic hypobaric hypoxia (CHH) by the indicators of the lipid peroxidation processes activity and the state of the antioxidant defense.Materials and methods. The studies were conducted under the conditions of CHH modeled by the standard method....
Subjects
free text keywords: antihypoxants; chronic hypobaric hypoxia; 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid derivative; mexidol, UDC 615.2:547.571’292:616.831-00, антигіпоксанти; хронічна гіпобарична гіпоксія; похідні 2-бензамідо-2(2-оксоіндолін-3-іліден) оцтової кислоти; мексидол, УДК 615.2:547.571’292:616.831-00, антигипоксанты; хроническая гипобарическая гипоксия; производные 2-бензамидо-2(2- оксоиндолин-3-илиден) уксусной кислоты; мексидол, Antioxidant, medicine.medical_treatment, medicine, Diabetes mellitus, medicine.disease, Hypoxia (medical), medicine.symptom, Acetic acid, chemistry.chemical_compound, chemistry, Biochemistry, Lipid peroxidation

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publication . Article . 2017

The effect of 2-benzamido-2-(2-oxoindolin-3-iliden) acetic acid derivative on the activity of lipid peroxidation processes and the antioxidant defense in chronic hypobaric hypoxia

I. I. Zamorskii; Yu. S. Bukataru; S. V. Kolisnyk;