publication . Part of book or chapter of book . 2011

Genetic Predisposition to Cutaneous Squamous Cell Carcinoma

Ng, Yi-Zhen; Dayal, Jasbani H.S; South, Andrew P.;
Open Access
  • Published: 14 Nov 2011
  • Publisher: InTech
Abstract
Ultraviolet (UV) radiation is the most ubiquitous mutagen known and as a direct result the skin is by far the most common site for cancer in Caucasian populations. In United Kingdom, non-melanoma skin cancer (NMSC) is the most frequent occurring cancer registration with over 98,854 cases in 2008, although estimates place it higher due to underreporting (CRUK, 2011a). Approximately three-quarters of NMSC are benign basal cell carcinomas (BCCs), while the remaining quarter consists predominantly of cutaneous squamous cell carcinomas (cSCC). NMSC accounts for 1 in 4 skin cancer deaths, the majority of which is attributed to the more malignant cSCC (Office for Natio...
Subjects
free text keywords: Xeroderma pigmentosum, medicine.disease, medicine, Oncology, medicine.medical_specialty, PTCH1, Metastasis, Mortality rate, Cancer, Internal medicine, Population, education.field_of_study, education, Skin cancer, Genetic predisposition, business.industry, business
Download fromView all 2 versions
https://www.intechopen.com/cit...
Part of book or chapter of book
Provider: UnpayWall
InTech
Part of book or chapter of book . 2011
Provider: InTech
http://www.intechopen.com/down...
Part of book or chapter of book . 2011
Provider: Crossref
197 references, page 1 of 14

Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, et al. (2011) Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science Epub 2011 Jul 28. doi: 10.1126/science.1206923. [OpenAIRE]

Alter BP (2003) Cancer in Fanconi anemia, 1927-2001. Cancer 97:425-440.

Alter BP, Olson SB (2009) Wilms tumor, AML, and medulloblastoma in a child with cancer prone syndrome of total premature chromatid separation and Fanconi anemia. Pediatr Blood Cancer 54:488; author reply 489.

Arbiser JL, Fine JD, Murrell D, Paller A, Connors S, Keough K, et al. (1998) Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa. Mol Med 4:191-195. [OpenAIRE]

Arbiser JL, Fan CY, Su X, Van Emburgh BO, Cerimele F, Miller MS, et al. (2004) Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma. J Invest Dermatol 123:788-790. [OpenAIRE]

Arita K, Wessagowit V, Inamadar AC, Palit A, Fassihi H, Lai-Cheong JE, et al. (2007) Unusual molecular findings in Kindler syndrome. Br J Dermatol 157:1252-1256. [OpenAIRE]

Arnault JP, Wechsler J, Escudier B, Spatz A, Tomasic G, Sibaud V, et al. (2009) Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib. J Clin Oncol 27:e59-61. [OpenAIRE]

Arron ST, Ruby JG, Dybbro E, Ganem D, Derisi JL (2011) Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma. J Invest Dermatol 131:1745-1753. [OpenAIRE]

Ashton GH, McLean WH, South AP, Oyama N, Smith FJ, Al-Suwaid R, et al. (2004) Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and photosensitivity disorder, Kindler syndrome. J Invest Dermatol 122:78-83.

Astori G, Lavergne D, Benton C, Hockmayr B, Egawa K, Garbe C, et al. (1998) Human Papillomaviruses are Commonly Found in Normal Skin of Immunocompetent Hosts. J Invest Dermatol 110:752-755. [OpenAIRE]

Baba Y, Iyama K, Honda S, Ishikawa S, Miyanari N, Baba H (2006) Cytoplasmic expression of type VII collagen is related to prognosis in patients with esophageal squamous cell carcinoma. Oncology 71:221-228.

Bagby GC, Jr. (2003) Genetic basis of Fanconi anemia. Curr Opin Hematol 10:68-76. [OpenAIRE]

Bagby GC, Alter BP (2006) Fanconi anemia. Semin Hematol 43:147-156.

Balmain A, Ramsden M, Bowden GT, Smith J (1984) Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature 307:658-660.

Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS, et al. (2010) Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res 70:5706-5716. [OpenAIRE]

197 references, page 1 of 14
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Part of book or chapter of book . 2011

Genetic Predisposition to Cutaneous Squamous Cell Carcinoma

Ng, Yi-Zhen; Dayal, Jasbani H.S; South, Andrew P.;