Physical Limitations to Tissue Engineering of Intervertabral Disc Cells

Part of book or chapter of book English OPEN
Kobayashi, Shigeru; Baba, Hisatoshi; Takeno, Kenichi; Miyazaki, Tsuyoshi; Meir, Adam; Urban, Jill;
  • Publisher: InTech

There is increasing interest in the using biological methods to repair degenerate discs. Biological repair depends on the disc maintaining a population of viable and active cells. Adequate nutrition of the disc influences the outcome of such therapies and, hence, must b... View more
  • References (161)
    161 references, page 1 of 17

    Aguiar, D.J.; Johnson, S.L. & Oegema, T.R. (1999). Notochordal cells interact with nucleus pulposus cells: Regulation of proteoglycan synthesis. Exp Cell Res, 246, 129-137.

    Alini, M.; Roughley, P.J. & Antoniou, J.; et al. (2002). A biological approach to treating disc degeneration: not for today, but maybe for tomorrow. Eur Spine J, 11, S215-S220.

    Alini, M.; Li, W.; Markovic, P.; et al. (2003). The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix. Spine, 28, 446-453.

    Alini, M.; Eisenstein, S.M.; Ito, K.; et al. (2008). Are animal models useful for studing human disc disorders/degeneration? Eur Spine J , 17, 2-19.

    Almarza, A.J. & Athanasiou, K.A. (2005). Effects of initial cell seeding density for the tissue engineering of the temporomandibular joint disc. Ann Biomed Eng, 33, 943-950.

    An, H.; Takegami, K.; Kamada, H.; et al. (2005). Intradiscal administration of osteogenic protein-1 increases intervertebral disc height and proteoglycan content in the nucleus pulposus in normal adolescent rabbits. Spine, 30, 25-31.

    Anderson, H. & Matthiessen, M.E. (1966). The histiocyte in human oetal tissues. Z Zellforsch Mikrock Anat, 72, 193-211.

    Baer, A.E.; Wang, J.Y.; Kraus, V.B.; et al. (2001). Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. J Orthop Res, 19, 2-10.

    Bassett, C.A.L. (1962). Current concepts of bone formation. J Bone Joint Surg, 44A, 1217-1244.

    Bayliss, M.T.; Johnstone, B.; O'Brien. J.P.; et al. (1988). Proteoglycan synthesis in the human intervertebral disc. Variation with age, region and pathology. Spine, 13, 972-981.

  • Related Organizations (1)
  • Metrics
Share - Bookmark

  • Download from
    InTech via InTech (Part of book or chapter of book, 2010)
  • Cite this publication