publication . Article . 2013

Amelioration of Sarcoptic Mange-Induced Oxidative Stress and Apoptosis in Dogs by Using Calendula officinalis Flower Extracts

Singh, Shanker K.; Dimri, Umesh;
Open Access
  • Published: 01 Jan 2013 Journal: ISRN Oxidative Medicine, volume 2,013, pages 1-8 (eissn: 2314-6400, Copyright policy)
  • Publisher: Hindawi Limited
Abstract
<jats:p>Twenty-four clinically <jats:italic>Sarcoptes</jats:italic>-infested dogs were randomly enrolled into three groups (groups A, B, and C), 8 dogs in each group. Group A was treated with ivermectin + <jats:italic>Calendula officinalis</jats:italic> flower extract (CFE). Group B was treated with ivermectin + N-acetyl cysteine (NAC) (standard positive controls), while group C (negative control) was treated with ivermectin alone. Another eight healthy dogs were used as healthy controls (group D). By day 28 after therapy, the dogs treated adjunctly with CFE as well as with N-acetyl cysteine revealed significant () amelioration of the altered markers of oxidativ...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Article Subject
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