publication . Article . Other literature type . 2012

Transdermal drug delivery: approaches and significance

Murthy, SATHYANARAYANA;
Open Access
  • Published: 03 May 2012 Journal: Research and Reports in Transdermal Drug Delivery (eissn: 2253-1580, Copyright policy)
  • Publisher: Dove Medical Press Ltd.
Abstract
Transdermal drug delivery systems deliver drugs through the skin as an alternative to oral, intravascular, subcutaneous, and transmucosal routes. Potential advantages of transdermal delivery include, but are not limited to, elimination of first-pass metabolism, steady delivery/blood levels, better patient compliance, reduced systemic drug interactions, possible dose intervention, avoidance of medically assisted drug administration, prolonged drug administration, and overall better therapeutic efficacy. Patches were the primitive form of transdermal drug delivery systems with conceptually simple engineering. The first representative of the transdermal drug delive...
Subjects
free text keywords: Research and Reports in Transdermal Drug Delivery

1. Cramer MP, Saks SR. Translating safety, efficacy and compliance into economic value for controlled release dosage forms. Pharmacoeconomics. 1994;5(6):482-504.

2. Henningfield JE. Nicotine medications for smoking cessation. N Engl J Med. 1995;333(18):1196-1203. [OpenAIRE]

3. Wallace MS, Ridgeway B, Jun E, Schulteis G, Rabussay D, Zhang L. Topical delivery of lidocaine in healthy volunteers by electroporation, electroincorporation, or iontophoresis: an evaluation of skin anesthesia. Reg Anesth Pain Med. 2001;26(3):229-238.

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