publication . Article . 2018

Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent

Xu,Li; Du,Jing; Wan,Caifeng; Zhang,Yu; Xie,Shaowei; Li,Hongli; Yang,Hong; Li,Fenghua;
Open Access English
  • Published: 01 Mar 2018 Journal: International Journal of Nanomedicine, volume 13, pages 1,791-1,807 (issn: 1176-9114, eissn: 1178-2013, Copyright policy)
  • Publisher: Dove Medical Press
Abstract
Li Xu,1,* Jing Du,1,* Caifeng Wan,1 Yu Zhang,1 Shaowei Xie,1 Hongli Li,1 Hong Yang,2 Fenghua Li1 1Department of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; 2Department of Chemistry, College of Life and Environmental Science, Shanghai Normal University, Shanghai, China *These authors contributed equally to this work Background: The development of nanoscale molecularly targeted ultrasound contrast agents (UCAs) with high affinity and specificity is critical for ultrasound molecular imaging in the early detection of breast cancer. Purpose: To prospectively evaluate ultrasound molecular imaging with dual-target...
Subjects
free text keywords: antibody, gold nanoshell, R5-920, breast cancer, poly (lactic-co-glycolic acid), International Journal of Nanomedicine, p53, VEGFR2, Medicine (General), ultrasound molecular imaging, Original Research, targeted ultrasound contrast agent, poly(lactic-co-glycolic acid)
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publication . Article . 2018

Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent

Xu,Li; Du,Jing; Wan,Caifeng; Zhang,Yu; Xie,Shaowei; Li,Hongli; Yang,Hong; Li,Fenghua;