Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts

Article English OPEN
Leung, Solomon;
(2008)
  • Publisher: Dove Press
  • Journal: International Journal of Nanomedicine (issn: 1178-2013)
  • Related identifiers: doi: 10.2147/IJN.S3234
  • Subject: International Journal of Nanomedicine

James C K Lai1, Maria B Lai1, Sirisha Jandhyam1, Vikas V Dukhande1, Alok Bhushan1, Christopher K Daniels1, Solomon W Leung21Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, and Biomedical Research Institute; 2Department of Civil and Environment... View more
  • References (38)
    38 references, page 1 of 4

    Ballabh P, Braun A, Nedergaard M. 2004. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis, 16:1-13.

    Bernard BK, Osheroff MR, Hofmann A, et al. 1990. Toxicology and carcinogenesis studies of dietary titanium dioxide-coated mica in male and female Fischer 344 rats. J Toxicol Environ Health, 29:417-29.

    Bröker LE, Kruyt FAE, Giaccone G. 2005. Cell death independent of caspases: a review. Clin Cancer Res, 11:3155-62.

    Chen JL, Fayerweather WE. 1988. Epidemiologic study of workers exposed to titanium dioxide. J Occup Med, 30:937-42.

    Clark JB, Lai JCK. 1989. Glycolytic, tricarboxylic acid cycle, and related enzymes in brain. In: Boulton AA, Baker GB, Butterworth RF (ed). NeuroMethods, Vol. 11. Clifton, NJ: Humana Press. p. 233-81.

    Dick CA, Brown DM, Donaldson K, et al. 2003. The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal Toxicol, 15:39-52.

    Dukhande VV, Malthankar-Phatak GH, Hugus JJ, et al. 2006. Manganese induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells. Neurochem Res, 31: 1349-1357.

    Garabrant DH, Fine LJ, Oliver C, et al. 1987. Abnormalities of pulmonary function and pleural disease among titanium metal production workers. Scand J Work Environ Health, 13:47-51.

    Golstein P, Kroemer G. 2007. Cell death by necrosis: towards a molecular definition. Trends Biochem Sci, 32:37-43.

    Gurr JR, Wang AS, Chen CH, et al. 2005. Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology, 213:66-73.

  • Similar Research Results (1)
  • Metrics
    No metrics available
Share - Bookmark