publication . Article . 2014

Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat

Thirunavukkarasu Thirumalai; Narayanaswamy Tamilselvan; Ernest David;
Open Access English
  • Published: 01 Jan 2014 Journal: Journal of Acute Disease (issn: 2221-6189, Copyright policy)
  • Publisher: Wolters Kluwer Medknow Publications
Abstract Objective To evaluate the hypolipidemic effect of Piper betel ( P. betel ) in high fat diet induced hyperlipidemia rat. Methods The methanol leaf extract was tested for hypolipidemic effect in the albino rats at the selected optimum dosage of 250 mg/kg body weight and administered orally. Adult male albino rats of six numbers in each group were undertaken study and evaluated. Results In group II animals, the activity levels of serum total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and very low density lipoprotein-cholesterol (VLDL) were significantly enhanced when compared to that of normal rat. Conclusion It could be said that ...
Medical Subject Headings: lipids (amino acids, peptides, and proteins)
free text keywords: Cardiovascular disease, Hyperlipidemia, Medicinal plant, Piper betel, High fat diet, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9, Fat diet, Betel, biology.organism_classification, biology, Low density, medicine.disease, medicine, Endocrinology, medicine.medical_specialty, Low-density lipoprotein, chemistry.chemical_compound, chemistry, Diabetes mellitus, Internal medicine, Piper, Very low-density lipoprotein
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