publication . Article . 2012

Protective effect of morin on lipid peroxidation and lipid profile in ammonium chloride–induced hyperammonemic rats

S Subash; P Subramanian;
Open Access
  • Published: 01 Apr 2012 Journal: Asian Pacific Journal of Tropical Disease, volume 2, pages 103-106 (issn: 2222-1808, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Abstract Objective To evaluated the protective effects of morin (3, 5, 7, 2′, 4′-pentahydroxyflavone) on lipid peroxidation and lipid levels during ammonium chloride (AC) induced hyperammonemia in experimental rats. Methods Thirty two male albino Wistar rats, which are weighing between 180–200 g were used for the study. The hyperammonemia was induced by administration of 100 mg/kg body weight ( i.p. ) thrice in a week of AC for 8 weeks. Rats were treated with morin at dose (30 mg/kg body weight) via intragastric intubations together with AC. At the end of experimental duration, blood ammonia, plasma urea, lipid peroxidation indices [thiobarbituric acid reactive ...
Subjects
Medical Subject Headings: lipids (amino acids, peptides, and proteins)
free text keywords: Microbiology (medical), Infectious Diseases, Virology, Thiobarbituric acid, chemistry.chemical_compound, chemistry, Antioxidant, medicine.medical_treatment, medicine, Lipid profile, medicine.diagnostic_test, Endocrinology, medicine.medical_specialty, Urea, Morin, Hyperammonemia, medicine.disease, Lipid peroxidation, Cholesterol, business.industry, business, Biochemistry, Internal medicine, Ammonium chloride, Ammonia, Lipids, R, Arctic medicine. Tropical medicine, RC955-962
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