publication . Article . 2002

Acetylsalicylic acid: Incoming 150 years of the first synthesis

Dušan Ž. Mijin; Slobodan D. Petrović; Milorad Blagojevic; Milena Stanković;
Open Access English
  • Published: 01 Jan 2002 Journal: Hemijska Industrija (issn: 0367-598X, Copyright policy)
  • Publisher: Association of Chemical Engineers of Serbia
Abstract
<jats:p>Acetylsalicylic acid is one of the most fascinating and versatile drugs known to medicine, as well as one of the oldest. Acetylsalicylic acid is a drug which is safe, with analgetic, antirheumatic, anti-inflammatory antiplatelet and antithrombotic action. It may be applied not only in clinical practice, but also as prevention. The first known use of an acetylsalicylic acid-like preparation can be traced to ancient Greece. In 1853 Charles Gerhardt published the first synthesis of acetylsalicylic acid. Felix Hoffmann, a chemist for Friedrich Bayer, a German dye company obtained a patent on acetylsalicylic acid some 40 years later. Bayer coined the name Asp...
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doi: 10.2298/hemind0210401m
Subjects
free text keywords: acetylsalicylic acid, properties, synthesis, purification, stability, mechanism of action, Chemical technology, TP1-1185, General Chemistry, General Chemical Engineering, Antithrombotic, Aspirin, medicine.drug, medicine, Chemistry, Clinical Practice, Pharmacology
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