GATE, a Geant4-based simulation platform for PET integrating movement and time management

Giovanni Santin; D Strul; D. Lazaro; Luc Simon; M. Krieguer; M. Vieira Martins; Vincent Breton; +1 Authors

Open Access

doi: 10.1109/nssmic.2002.1239563

Published: 10 Nov 2002

Publisher: IEEE

Country: France

- Summary
- References
  (10)

Abstract

GATE, the Geant4 Application for Tomographic Emission, is a simulation platform developed for PET and SPECT. It combines a powerful simulation core (the Geant4 toolkit) and a large range of developments dedicated to nuclear medicine. In particular, it models the passing of time during real acquisitions, allowing to handle dynamic systems such as decaying source distributions or moving detectors. We present several series of results that illustrate the possibilities of this new platform. The simulation of decaying sources is illustrated on a dual-isotope acquisition with multiple time-frames. Count rate curves taking into account random coincidences and dead-time are shown for a dual-crystal set-up and for a small-animal PET scanner configuration. Simulated resolution curves and reconstructed images are shown for rotating PET scanners. Lastly, we present comparisons of simulated point-spread functions and spectra with experimental results obtained from a small-animal gamma camera prototype.

Subjects by Vocabulary

Microsoft Academic Graph classification: Series (mathematics) Single-photon emission computed tomography medicine.diagnostic_test medicine Computer graphics (images) Gamma camera law.invention law Monte Carlo method Physics Large range Computational science Pet scanner Detector

arXiv: Physics::Medical Physics

ACM Computing Classification System: ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION

Related Organizations

This work was supported by the Swiss National Foundation for Research under Grant No. 21-63870.00.

D. Lazaro and V. Breton are with the Laboratoire de Physique Corpusculaire, IN2P3 - CNRS, University of Clermont-Ferrand, France (lazaro@clermont.in2p3.fr).

M. Vieira Martins is with the Institute of Biophysics and Biomedical Engineering, University of Lisbon, Portugal (d323@fc.ul.pt).

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imaging small animals,” IEEE Trans. Nucl. Sci 1997;44:1161-1166 [4] http://stir.irsl.org [5] A. F. Chatziioannou, S. R. Cherry, Y. Shao, R. W. Silverman, K.

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Archimandritis, D. Varvarigou et al., “A 3D high-resolution gamma

submitted [7] http://www-iphe.unil.ch/~PET/research/gate/

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