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IEEE Transactions on Medical Imaging
Article . 2025 . Peer-reviewed
License: CC BY NC ND
Data sources: Crossref
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Serveur académique lausannois
Article . 2025
License: CC BY NC ND
https://dx.doi.org/10.48620/85...
Other literature type . 2025
Data sources: Datacite
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Multi-Label Generalized Zero Shot Chest X-Ray Classification by Combining Image-Text Information With Feature Disentanglement

Authors: Dwarikanath Mahapatra; Antonio Jimeno Yepes; Behzad Bozorgtabar; Sudipta Roy; Zongyuan Ge; Mauricio Reyes;

Multi-Label Generalized Zero Shot Chest X-Ray Classification by Combining Image-Text Information With Feature Disentanglement

Abstract

In fully supervised learning-based medical image classification, the robustness of a trained model is influenced by its exposure to the range of candidate disease classes. Generalized Zero Shot Learning (GZSL) aims to correctly predict seen and novel unseen classes. Current GZSL approaches have focused mostly on the single-label case. However, it is common for chest X-rays to be labelled with multiple disease classes. We propose a novel multi-modal multi-label GZSL approach that leverages feature disentanglement andmulti-modal information to synthesize features of unseen classes. Disease labels are processed through a pre-trained BioBert model to obtain text embeddings that are used to create a dictionary encoding similarity among different labels. We then use disentangled features and graph aggregation to learn a second dictionary of inter-label similarities. A subsequent clustering step helps to identify representative vectors for each class. The multi-modal multi-label dictionaries and the class representative vectors are used to guide the feature synthesis step, which is the most important component of our pipeline, for generating realistic multi-label disease samples of seen and unseen classes. Our method is benchmarked against multiple competing methods and we outperform all of them based on experiments conducted on the publicly available NIH and CheXpert chest X-ray datasets.

Keywords

Databases, Factual, Humans, Radiographic Image Interpretation, Computer-Assisted, Radiography, Thoracic, Humans; Radiography, Thoracic/methods; Algorithms; Radiographic Image Interpretation, Computer-Assisted/methods; Databases, Factual, Supervised Machine Learning, Algorithms

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
hybrid