Based on the social, legal and economic implications imposed by globalization, as well as the integration between nations, this paper proposes to discuss the concept of development by analyzing the constitutions of Brazil, Paraguay, Argentine, and Chile, considering that a debate between academia and other institutions emerges in the Latin America integration context. This is an urgent and necessary dialogue to guide possible courses for this region. Countries from the most diverse continents already indicate a break in customs tariffs and the rise of new economic agreements, bringing countries of the Latin-American Integration Route (RILA) closer to the countries of today's greatest and most solid economic bloc, the European Union. This sets a precedent for the idea that RILA is becoming a macro-territory of increasing economic, social and legal visibility, which is a reason why thinking about regional development is a priority task, as well as drawing up studies and reflections that lead to a possible harmonization and integration of legal norms. These are tasks of the governments, academia, companies, and civil society. Furthermore, the present work discusses the need for legal grounds involving countries that make up the RILA, in order to provide greater legal security and dignity for the subjects involved in this intense process.