In a world where effective communication is fundamental, individuals who are Deaf and Dumb (D&D) often face unique challenges due to their primary mode of communication—sign language. Despite the interpreters' invaluable roles, their lack of availability causes communication difficulties for the D&D individuals. This study explores whether the field of Human-Computer Interaction (HCI) could be a potential solution. The primary objective is to assist D&D individuals with computer applications that could act as mediators to bridge the communication gap between them and the wider hearing population. To ensure their independent communication, we propose an automated system that could detect specific Bangla Sign Language (BdSL) words, addressing a critical gap in the sign language detection and recognition literature. Our approach leverages deep learning and transfer learning principles to convert webcam-captured hand gestures into textual representations in real-time. The model's development and assessment rest upon 992 images created by the authors, categorized into ten distinct classes representing various BdSL words. Our findings show the DenseNet201 and ResNet50-V2 models achieve promising training and testing accuracies of 99% and 93%, respectively. Doi: 10.28991/ESJ-2023-07-06-019 Full Text: PDF