A clinical case of endovascular correction of a biological mitral valve prosthesis dysfunction by implantation of a transcatheter aortic valve into the mitral position is described. Considering the clinical status of the patient, the condition was determined to be inoperable. Subsequently, based on vital fluoroscopy and echocardiography findings, the patient was implanted with a transcatheter aortic valve in the mitral valve bioprosthesis position. The technical and clinical aspects of the intervention and its results were analysed during the hospital period and for 5 months after implantation. The selected method of treatment was found to be appropriate.Received 10 January 2020. Revised 18 March 2020. Accepted 19 March 2020.Funding: The study did not have sponsorship.Conflict of interest: Authors declare no conflict of interest.Author contributionsDrafting the article: N.V. Rogulina, I.V. Ganyukov, A.M. Kochergina, V.I. Ganyukov, R.S. Tarasov, I.K. Khalivopulo, I.N. Sizova Literature review: V.I. Ganyukov, R.S. Tarasov, N.V. Rogulina, I.K. Khalivopulo, I.V. Ganyukov, A.M. Kochergina Illustrations: I.V. Ganyukov, I.N. Sizova, N.V. Rogulina Critical revision of the article: V.I. Ganyukov, R.S. Tarasov, E.A. Shloido, L.S. Barbarash Surgical treatment: E.A. Shloido, V.I. Ganyukov, R.S. TarasovFinal approval of the version to be published: V.I. Ganyukov, E.A. Shloido, R.S. Tarasov, N.V. Rogulina, I.K. Khalivopulo, I.V. Ganyukov, A.M. Kochergina, I.N. Sizova, L.S. Barbarash