Biofeedback is the process of gaining greater awareness of many physiological functions primarily using instruments that provide information on the activity of those systems, with a goal of being able to manipulate them at will. In this work, the analysis of efficiency of biofeedback therapy in treatment of patients suffering from rheumatoid arthritis (RA) is carried out. This analysis was fulfilled by studying the dynamics of clinical, laboratory and psychological before and after the treatment. During the course of combined therapy alongside biofeedback therapy, an increase in analgesic and anti-inflammatory reactions, improved functional capabilities and an improved sign in the formation of personal positive traits were noticed in the patients. Thus, the additional use of biofeedback mechanism in complex treatment of RA patients promotes increased efficiency of medical and rehabilitation process and improvement of level of self-control in the patients.