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CLINICAL EVIDENCE FOR THE EFFECTIVENESS OF OLEOPREN NEYRO DIETARY SUPPLEMENT IN PREVENTION AND COMPREHENSIVE TREATMENT OF DYSCIRCULATORY ENCEPHALOPATHY OF VASCULAR GENESIS

КЛИНИЧЕСКИЕ ДОКАЗАТЕЛЬСТВА ЭФФЕКТИВНОСТИ БАД «ОЛЕОПРЕН НЕЙРО» В ПРОФИЛАКТИКЕ И КОМПЛЕКСНОМ ЛЕЧЕНИИ ДИСЦИРКУЛЯТОРНОЙ ЭНЦЕФАЛОПАТИИ СОСУДИСТОГО ГЕНЕЗА
Authors: Shamova, M.M.; Mukhametova, Yu.R.; Avstriyevskikh, А.N.;

CLINICAL EVIDENCE FOR THE EFFECTIVENESS OF OLEOPREN NEYRO DIETARY SUPPLEMENT IN PREVENTION AND COMPREHENSIVE TREATMENT OF DYSCIRCULATORY ENCEPHALOPATHY OF VASCULAR GENESIS

Abstract

Clinical trials of effectiveness and functional orientation of a special product – Oleopren Neyro dietary supplement – on a representative group of patients with dyscirculatory encephalopathy of vascular genesis of stages I – II are carried out. The product has been included in the patients’ diet along with basic therapy in a dose of one capsule twice a day during 10 days. Indexes of clinical symptoms and signs such as: general physical and mental state of the patients, headache, process of memorizing and recalling reads, initiative, attentiveness and concentration, emotional-volitional sphere, muscular tone, hypertensive syndrome, electroencephalogram (EEG), rheoencephalogram are studied along with the indexes of life quality: energy level, sensation of pain, emotional condition, sleep, social isolation, physical activity. As a result of the therapy, distinct positive dynamics of clinical disease is registered: general condition of 95 % of patients has improved. After treatment with the use of nutrition factor, short-term memory capacity has increased, the majority of patients can correctly repeat 10 words; average time for completing a task for attention concentration has decreased from 61,1 seconds before the beginning of the treatment to 43,5 seconds in the control group and 40,6 in the group of patients with dyscirculatory encephalopathy who have been taking Oleopren Neyro, on completing the therapy (Р < 0,05). The obtained research results give grounds for recommending the dietary supplement as an effective agent for enhancing body resistance to adverse effect of the environment, stressful situations, psychoemotional and physical exertions. Test product can be used in comprehensive treatment, and in order to prevent encephalopathy of different nature (residual, vascular, post-traumatic, toxical). Possible influence of nutrition factor on metabolism correction, connected with functional disorder of dolichol phosphate cycle at the cell membrane level, increased removal of dolichols from the body and promotion of their deficiency, is studied. Polypropenols as a part of dietary supplement composition hold key positions in the dolichol phosphate cycle and provide biosynthesis of glycoproteins and glucoaminoglukans, glycosylation of membrane proteins, preventing their proteolysis.

Keywords

дисциркуляторная энцефалопатия, полипренолы, functional orientation, функциональная направленность, comprehensive treatment, эффективность, комплексное лечение, effectiveness, dyscirculatory encephalopathy, профилактика, dietary supplement, nutrition correction, preventive treatment, polyprenols, коррекция питания, УДК 613.8.293, diet, рацион, dolichol phosphate cycle, БАД, долихол-фосфатный цикл

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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