One of the most dynamically developing areas of knowledge is modern medicine. In many ways, the pace of development of medicine is determined by technological capabilities. The blood service is one of the most technologically saturated branches of medicine since the quality of the final product and the patient’s health depend on the processing technology of the blood and its components. According to the technical regulations on the safety requirements of blood, its products, blood-substituting solutions and technical means used in transfusion-infusion therapy, approved by the Government of Russia on 01/26/2010: “The components of donated blood must be thawed and heated to the required temperature using specially designed equipment”. Defroster for cryopreserved blood products are specialized technical means used to measure electrical, magnetic and electromagnetic quantities characterizing the temperature parameters of the object to be thawed and heated. In the field of defrosting and heating cryopreserved blood products for transfusion-infusion, the fundamental task is to develop a software solution for simulating defrosting systems, which can make it possible to determine the optimal parameters of defrosting systems at the stage of pre-model modeling. This article describes an experimental study to evaluate the phase transition of an ice-liquid plasma during defrosting using radio measuring equipment. The obtained data will be used to create a mathematical model of the process of defrosting blood products.