Despite the reduced demand for fiber boards, research related to their manufacture is relevant, since the production of wood-based materials significantly contributes to solving the problem of the integrated use of wood raw materials. The paper presents the results of experimental studies reflecting the dependence of the strength characteristics of dry and wet wood fiber boards on the structural and technological parameters of grinding plants of various modifications. The experiments were carried out in laboratory facilities and in the production environment on existing industrial equipment. Based on the results of processing multifactor experiments implemented in a second-order B plan, a mathematical description was obtained of the dependence of the tensile strength during static bending of solid wood fiber boards of the dry and wet production method on the gap between the grinding disks, wear of the segments and the concentration of wood fiber mass. The obtained regression models are adequate to the process and can be applied in practice to predict the strength characteristics of fiberboards depending on the parameters of the grinding process. As a result of the analysis of the calculated and graphical dependences obtained on the basis of studies in the production environment on the existing equipment, it is possible to determine what parameters on the grinding equipment must be set in order to obtain the necessary physical and mechanical properties of the fiberboard.