Purpose. Brief presentation of the distinguished achievements of Nobel Prize Laureates in physics for current time period of 2016-2019. Methodology. Scientific methods of collection, analysis and analytical treatment of scientific and technical information of world level in area of astronomy, astrophysics, physicists of the condensed environments, laser physics, modern theoretical and experimental physics. Results. The brief analytical review of the scientific discovery and distinguished achievements of scientists-physicists in area of modern physical and technical problems which were marked the Nobel Prizes in physics for the period 2016-2019 is presented. In the number of such discovery and achievements of the best representatives of world scientific association entered: theoretical discovery of topology phase transitions and topology phases of matter, experimental discovery of gravity waves, revolutionary inventions in area of laser physics, astronomic discovery and contribution to our understanding of evolution of Universe and place of Earth in space. Originality. Systematization and analytical exposition is executed in short concentrated and accessible to the wide reader to the form of the known scientific and technical materials, awarded with the Nobel Prizes in physics for current time period of 2016-2019 and devoted to: the theoretical openings of topology phase transitions and topology phases of matter, experimental opening of gravity waves, revolutionary inventions in area of laser physics, astronomic discovery and contribution to our understanding of evolution of Universe and place of Earth in space. Practical value. Popularization and deepening of scientific and technical knowledge for students, engineer and technical specialists and research workers in area of astronomy, astrophysics, physicists of the condensed environments, laser physics, modern theoretical and experimental physics, extending their scientific range of interests and further development of scientific and technical progress in human society.