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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Zeitschrift für anor...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Zeitschrift für anorganische und allgemeine Chemie
Article . 2021
License: Wiley Online Library User Agreement
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One‐pot synthesis of ICG&Cur@ZIF‐8 nanocomposites with pH‐controlled drug delivery and good photothermal performance

Authors: Yifei Su; Weishu Ni; Haiyan Zhang; Ke Jiang; Feng Wen;

One‐pot synthesis of ICG&Cur@ZIF‐8 nanocomposites with pH‐controlled drug delivery and good photothermal performance

Abstract

AbstractCombination therapy has shown great potential for effective cancer treatment. In this work, anticancer drug curcumin (Cur) and photothermal agent indocyanine green (ICG) have been encapsulated into the pH‐responsive ZIF‐8 simultaneously to obtain ICG&Cur@ZIF‐8 through one‐pot synthesis method. The drug loading capacity was estimated as 9.6 and 12.3 wt% for Cur and ICG, respectively. As expected, ICG&Cur@ZIF‐8 exhibited the pH‐responsive ICG and Cur delivery, which was ascribed to the decomposition of ZIF‐8 in acidic environment. Moreover, ICG&Cur@ZIF‐8 also showed the high photothermal performance due to the efficient encapsulation of ICG. The co‐delivery of two therapeutic agents may bring more opportunities for biomedical application.

Related Organizations
Keywords

Inorganic Chemistry

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    4
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Top 10%
Average
Average
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