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Publication . Article . 2019

Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

Chaolong Wu; Xiaoyu Huang; Yunyun Tang; Wanyue Xiao; Liguo Sun; Jinjun Shao; Xiaochen Dong;
Closed Access
Published: 01 Jan 2019 Journal: Chemical Communications, volume 55, pages 790-793 (issn: 1359-7345, eissn: 1364-548X, Copyright policy )
Publisher: Royal Society of Chemistry (RSC)
A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg-1).
Subjects by Vocabulary

Microsoft Academic Graph classification: Cancer therapy In vivo Microscopy Photoacoustic Techniques Transplantation Photothermal therapy Materials science Near-infrared spectroscopy Photochemistry Photosensitizer

Medical Subject Headings: technology, industry, and agriculture neoplasms equipment and supplies surgical procedures, operative food and beverages


Materials Chemistry, Metals and Alloys, Surfaces, Coatings and Films, General Chemistry, Ceramics and Composites, Electronic, Optical and Magnetic Materials, Catalysis

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