publication . Article . 2012

Quality control of 5mg diazepam suppositories manipulated in the city of Campos Goytacazes - RJ

Renata Aparecida Venturi Canzian; Fernanda Fraga Pessanha; Jean Carlos Brandão Storck;
Open Access
  • Published: 01 Oct 2012 Journal: Revista Vértices, volume 14, pages 263-270 (issn: 1809-2667, Copyright policy)
  • Publisher: Essentia Editora
Abstract
<em>Diazepam suppositories are widely used by children and elderly, and require close attention to quality control because it is a controlled prescription drug. The objective of the study was to analyze diazepam suppositories manipulated in Campos dos Goytacazes, RJ, to verify if they are within the required quality standards, and offer safety and efficiency to patients. We analyzed samples of 5mg diazepam suppositories acquired in five randomly selected pharmacies, identified as Pharmacy A, Pharmacy B, Pharmacy C, Pharmacy D, and Pharmacy E. We ran tests on average weight, organoleptic control, hardness, melting point, and dissolution. Data was analyzed and com...
Subjects
free text keywords: Suppository. Diazepam. Quality control., Science (General), Q1-390, Social sciences (General), H1-99
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