publication . Other literature type . Article . 2018

Fungicidal PMMA-Undecylenic Acid Composites.

Milica Petrović; Debora Bonvin; Heinrich Hofmann; Marijana Mionić Ebersold;
Open Access
  • Published: 08 Jan 2018
  • Publisher: MDPI AG
  • Country: Switzerland
Abstract
Undecylenic acid (UA), known as antifungal agent, still cannot be used to efficiently modify commercial dental materials in such a way that this affects Candida. Actually, issues with Candida infections and fungal resistance compromise the use of Poly(methyl-methacrylate) (PMMA) as dental material. The challenge remains to turn PMMA into an antifugal material, which can ideally affect both sessile (attached) and planktonic (free-floating) Candida cells. We aimed to tackle this challenge by designing PMMA-UA composites with different UA concentrations (3–12%). We studied their physico-chemical properties, the antifungal effect on Candida and the cytotoxicity towa...
Subjects
free text keywords: Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Spectroscopy, Molecular Biology, Catalysis, General Medicine, Computer Science Applications, undecylenic acid, PMMA, antifungal, fungicidal, anti-Candida, Candida albicans, Biology (General), QH301-705.5, Chemistry, QD1-999, Article
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