Oxidative stress and Parkinson’s Disease

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Javier eBlesa; Javier eBlesa; Javier eBlesa; Ines eTrigo-Damas; Ines eTrigo-Damas; Anna eQuiroga-Varela; Vernice Ruffin Jackson-Lewis;
(2015)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Neuroanatomy (issn: 1662-5129)
  • Related identifiers: doi: 10.3389/fnana.2015.00091/full, doi: 10.3389/fnana.2015.00091
  • Subject: QM1-695 | Human anatomy | Neurosciences. Biological psychiatry. Neuropsychiatry | Neuroinflammation | RC321-571 | Mitochondrial dysfunction | Parkinson Disease | Dopamine | Oxidative Stress
    mesheuropmc: nervous system

Parkinson disease is a chronic, progressive neurological disease that is associated with a loss of dopaminergic neurons in the substantia nigra of the brain. The molecular mechanisms underlying the loss of these neurons still remain elusive. Oxidative stress is thought ... View more
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