Palmitic Acid Curcumin Ester Facilitates Protection of Neuroblastoma against Oligomeric Aβ40 Insult

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Zhangyang Qi; Meihao Wu; Yun Fu; Tengfei Huang; Tingting Wang; Yanjie Sun; Zhibo Feng; Changzheng Li;
  • Publisher: Cell Physiol Biochem Press GmbH & Co KG
  • Journal: Cellular Physiology and Biochemistry (issn: 1015-8987, eissn: 1421-9778)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1159/000485117
  • Subject: Curcumin derivatives | ROS scavenger | Interaction | Liposome | Amyloid beta | Spectral titration | Physiology | QP1-981 | Biochemistry | QD415-436

Background/Aims: The generation of reactive oxygen species (ROS) caused by amyloid-β (Aβ) is considered to be one of mechanisms underlying the development of Alzheimer’s disease. Curcumin can attenuate Aβ-induced neurotoxicity through ROS scavenging, but the protective ... View more
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