publication . Article . 2004

HLA alleles and lung cancer in a Turkish population.

Ozbek N; Birinci A; Karaoglanoglu O; Coban Ahmet; Okumus B; Cakir S; Durupinar B;
Open Access
  • Published: 01 Jan 2004 Journal: Annals of Saudi Medicine, volume 24, pages 106-111 (issn: 0256-4947, eissn: 0975-4466, Copyright policy)
  • Publisher: King Faisal Specialist Hospital and Research Centre
Abstract
BACKGROUND: The concept of genetic factors playing a role in the pathogenesis of lung cancer has gained increased attention. The present study was undertaken to examine the question of HLA association with lung cancer and to investigate the effects of HLA on survival time. METHODS: The distribution of HLA class I (A, B, C) antigens and class II (DR, DQ) alleles were studied in 81 unrelated Turkish patients with lung cancer. The HLA status of patients was compared with that of a control group consisting of 117 ethnically matched healthy donors. HLA class I antigens were studied by Terasaki′s microlymphocytotoxicity test and HLA class II alleles were studie...
Subjects
free text keywords: General Medicine, Intensive care medicine, medicine.medical_specialty, medicine, Allele, Case-control study, business.industry, business, Prospective cohort study, Human leukocyte antigen, Allele frequency, Adenocarcinoma, medicine.disease, Turkish population, Immunology, Lung cancer, epidemiology, genetics, Adult, Aged, 80 and over, Analysis of Variance, Carcinoma, Small Cell, Squamous Cell, R
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