publication . Article . 2014

Persistent hepatitis virus infection and immune homeostasis

ZHOU Yun;
Open Access Chinese
  • Published: 01 Sep 2014 Journal: Linchuang Gandanbing Zazhi (issn: 1001-5256, eissn: 1001-5256, Copyright policy)
  • Publisher: Editorial Department of Journal of Clinical Hepatology
Abstract
Homeostasis between the host and viruses is naturally maintained. On the one hand, the immune system activates the immune response to kill or eliminate viruses; on the other hand, the immune system controls the immune response to maintain immune homeostasis. The cause of persistent infections with hepatitis viruses such as HBV and HCV is that viral molecules damage the immune system of the host and their variants escape immune clearance. Long-term coexistence of the host and viruses is the process involving various immune cells and molecules and is the result of homeostasis maintenance in antiviral immune response. The immune homeostasis maintained during persis...
Subjects
Medical Subject Headings: biochemical phenomena, metabolism, and nutritionbacteriachemical and pharmacologic phenomenaanimal diseasesviruses
free text keywords: hepatitis viruses; immune system; allostasis, Diseases of the digestive system. Gastroenterology, RC799-869
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