publication . Article . 2016

Immunohistochemical Analysis of Platelet Extract Effects on Liver Injury Induced by CCl4 in Male Rats

Zahra Hesami; Maryam Ayatollahi; Bita Geramizadeh; Akram Jamshidzadeh; Akbar Vahdati;
Open Access Persian
  • Published: 01 Jan 2016 Journal: Journal of Ardabil University of Medical Sciences (issn: 2228-7280, eissn: 2228-7299, Copyright policy)
  • Publisher: Ardabil University of Medical Sciences
Abstract
Backgrounds & objectives: Liver damage results in a large accumulation of external cellular matrix that affects the function of this important body organ in a long term and finally stops its function completely. The growth factors existing in platelet extract are more cost-effective, available, and stable than recombinant ones. To determine whether the platelet extract effects on histological changes in liver injury induced by carbon tetrachloride (CCl4), we used immunohistochemical analysis in male rats. Methods: In this project the 28 male Wistar rats (250-300 g) were randomly divided into 4 groups, each consisting of 7 animals. The rats were divided into four...
Subjects
free text keywords: Liver Injury, Immunohistochemistry, CCl4, Platelet Extract, Rat, Medicine (General), R5-920
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