publication . Article . 2013

Experimental Model of Spinal Cord Injury (SCI) in rats: management guidelines Modelo Experimental de Lesión de Médula Espinal (SCI) en ratas: guías de manejo Modelo Experimental de Lesão Medular (SCI) em ratos: diretrizes de manejo

Asdrubal Falavigna; Fernanda Cechetti; Guilherme Finger; Leonardo Gilmone Ruschel; Grasiela Marcon; Pedro Guarise da Silva;
Open Access English
  • Published: 01 Jan 2013 Journal: Coluna/Columna (issn: 1808-1851, eissn: 2177-014X, Copyright policy)
  • Publisher: Sociedade Brasileira de Coluna (SBC)
Abstract
Surgical experiments with laboratory animals are necessary for medical research. These studies aim to clarify the mechanism of disease, investigate the action and efficacy of new drugs or biological markers, as well as develop and enhance new therapies and apply new techniques. Regarding the models of spinal cord injury (SCI), there are several different methods that address the handling of the animals, especially concerning the use of analgesics, antibiotics and pre- and postoperative management. The lack of uniformity and standardization among the studies does not allow the understanding of the model of SCI or the proper handling of the paraplegic animals, ham...
Subjects
free text keywords: Modelos animales, Traumatismos de la médula espinal, Paraplejía, Investigación biomédica, Modelos animais, Traumatismos da medula espinal, Paraplegia, Pesquisa biomédica, Models, Animal, Spinal cord injuries, Paraplegia, Biomedical research, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935
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Article . 2013
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