publication . Article . 2014

Focal Dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE)

David ePerruchoud; Micah M Murray; Micah M Murray; Jeremie eLefebvre; Silvio eIonta;
Open Access English
  • Published: 01 Jun 2014 Journal: Frontiers in Human Neuroscience (issn: 1662-5161, Copyright policy)
  • Publisher: Frontiers Media S.A.
Performing accurate movements requires preparation, execution, and monitoring mechanisms. The first two are coded by the motor system, and the latter by the sensory system. To provide an adaptive neural basis to overt behaviors, motor and sensory information has to be properly integrated in a reciprocal feedback loop. Abnormalities in this sensory-motor loop are involved in movement disorders such as focal dystonia, a hyperkinetic alteration affecting only a specific body part and characterized by sensory and motor deficits in the absence of basic motor impairments. Despite the fundamental impact of sensory-motor integration mechanisms on daily life, the general...
free text keywords: Behavior, Movement Disorders, Rehabilitation, fMRI, inhibition, modeling, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
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