publication . Article . Other literature type . 2018

Genetic and Virulent Difference Between Pigmented and Non-pigmented Staphylococcus aureus.

Fangning Jin; Dao-Feng Zhang; Jing Zhang; Hang Zhao; Chunlei Shi; Yujuan Suo;
Open Access English
  • Published: 01 Apr 2018 Journal: Frontiers in Microbiology (issn: 1664-302X, Copyright policy)
  • Publisher: Frontiers Media S.A.
Abstract
Staphyloxanthin (STX), a golden carotenoid pigment produced by Staphylococcus aureus, is suggested to act as an important virulence factor due to its antioxidant properties. Restraining biosynthesis of STX was considered as an indicator of virulence decline in pigmented S. aureus isolates. However, it is not clear whether natural non-pigmented S. aureus isolates have less virulence than pigmented ones. In this study, it is aimed to compare the pigmented and non-pigmented S. aureus isolates to clarify the genetic and virulent differences between the two groups. Here, 132 S. aureus isolates were divided into two phenotype groups depending on the absorbance (OD450)...
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doi: 10.3389/fmicb.2018.00598/full , 10.3389/fmicb.2018.00598
pmc: PMC5891619
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Subjects
Medical Subject Headings: sense organs
free text keywords: Staphylococcus aureus, staphyloxanthin, non-pigmented, virulence, murine sepsis model, Microbiology, QR1-502, Original Research, Microbiology (medical), Multilocus sequence typing, medicine.disease_cause, medicine, Gene, Phenotype, Biology, Virulence factor, Carotenoid, chemistry.chemical_classification, chemistry, chemistry.chemical_compound
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