publication . Article . 2009

Rise, fall and resurrection of chromosome territories: a historical perspective. Part I. The rise of chromosome territories

T Cremer; C Cremer;
Open Access English
  • Published: 01 Jun 2009 Journal: European Journal of Histochemistry (issn: 1121-760X, eissn: 2038-8306, Copyright policy)
  • Publisher: PAGEPress Publications
Abstract
It is now generally accepted that chromosomes in the cell nucleus are organized in distinct domains, first called chromosome territories in 1909 by the great cytologist Theodor Boveri. Yet, even today chromosomes have remained enigmatic individuals, whose structures, arrangements and functions in cycling and post-mitotic cells still need to be explored in full detail. Whereas numerous recent reviews describe present evidence for a dynamic architecture of chromosome territories and discuss the potential significance within the functional compartmentalization of the nucleus, a comprehensive historical account of this important concept of nuclear organization was l...
Subjects
free text keywords: Biology (General), QH301-705.5
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