High Mobility Group Box1 Inhibitor Glycyrrhizic Acid Attenuates Kidney Injury in Streptozotocin-Induced Diabetic Rats

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Hong Zhang; Ru Zhang; Juan Chen; Min Shi; Wei Li; Xiangcheng Zhang;
  • Publisher: Karger Publishers
  • Journal: Kidney & Blood Pressure Research (issn: 1420-4096, eissn: 1423-0143)
  • Related identifiers: doi: 10.1159/000485045
  • Subject: High mobility group box 1 | Diabetic kidney disease | Inflammation | Glycyrrhizic acid | Dermatology | RL1-803 | Diseases of the circulatory (Cardiovascular) system | RC666-701 | Diseases of the genitourinary system. Urology | RC870-923

Background/Aims: High mobility group box 1 (HMGB1) is an important mediator of the inflammatory response. It has been implicated in the pathogenesis of autoimmune diseases, atherosclerosis, and obesity. However, the effects of HMGB1 on diabetic nephropathy remain unclea... View more
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