Skin changes in chronic kidney disease

Article English OPEN
Joanna M. Przepiórka-Kosińska ; Katarzyna M. Chyl-Surdacka ; Joanna Bartosińska ; Dorota Krasowska ; Grażyna Chodorowska (2017)
  • Publisher: Termedia Publishing House
  • Journal: Przegląd Dermatologiczny (issn: 0033-2526, eissn: 2084-9893)
  • Related identifiers: doi: 10.5114/dr.2017.67389
  • Subject: chronic kidney disease | pseudoporphyria | nephrogenic systemic fibrosis | kidney failure | Medicine | cutaneous manifestations | R | acquired perforating dermatosis | Dermatology | calciphylaxis | porphyria cutanea tarda | RL1-803
    mesheuropmc: skin and connective tissue diseases | sense organs | integumentary system

Chronic kidney disease causes skin changes which may sometimes be the first sign of kidney failure. Specific skin changes include acquired perforating dermatosis, porphyria cutanea tarda, pseudoporphyria, calcinosis and nephrogenic systemic fibrosis. The majority of patients present with cutaneous manifestations which are classified as non-specific, including xerosis, pruritus, pigmentation disturbances, nail plate abnormalities, uraemic frost and gynaecomastia. Treatment improving kidney function (dialysis therapy or kidney transplantation) also leads to the resolution of skin lesions.
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