Phospholipid-Coated Mesoporous Silica Nanoparticles Acting as Lubricating Drug Nanocarriers

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Tao Sun; Yulong Sun; Hongyu Zhang;
  • Publisher: MDPI AG
  • Journal: Polymers (issn: 2073-4360)
  • Related identifiers: doi: 10.3390/polym10050513
  • Subject: osteoarthritis | mesoporous silica nanoparticles | phospholipids | hydration lubrication | drug delivery | Organic chemistry | QD241-441

Osteoarthritis (OA) is a severe disease caused by wear and inflammation of joints. In this study, phospholipid-coated mesoporous silica nanoparticles (MSNs@lip) were prepared in order to treat OA at an early stage. The phospholipid layer has excellent lubrication capabi... View more
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