publication . Article . 2008

Sustained-release calcium antagonist in patients over 60 years with isolated and systolo-diastolic arterial hypertension

V. E. Oleynikov; V. A. Budanova; E. E. Grishaeva; E. I. Yastrebova; S. S. Fadeeva; L. I. Gusakovskaya;
Open Access Russian
  • Published: 01 Dec 2008 Journal: Кардиоваскулярная терапия и профилактика (issn: 1728-8800, eissn: 2619-0125, Copyright policy)
  • Publisher: «SILICEA-POLIGRAF» LLC
Abstract
Aim. To study antihypertensive and organo-protective effects of a calcium antagonist (CA), controlled-release (CR) nifedipine, in patients over 60 years with Stage I-II isolated systolic and systolo-diastolic arterial hypertension (ISAH, SDAH).Material and methods. This 24-week open prospective study included 48 patients aged over 60 years with Stage I-II AH. SDAH and ISAH participants received nifedipine SR in the dose of 40 mg/d. Treatment effectiveness was assessed by dynamics of office blood pressure (BP) and 24-hour BP monitoring (BBP) parameters. Organoprotective effect was assessed by dynamics of echocardiography parameters and microalbuminuria (MAU) leve...
Subjects
free text keywords: sustained-release nifedipine, isolated systolic arterial hypertension, hypertension in the elderly, microalbuminuria in the elderly, Diseases of the circulatory (Cardiovascular) system, RC666-701
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